March Madness second-round prediction: Princeton vs. Missouri pick

Princeton pulled off the unthinkable by defeating No. 2 seed Arizona during the first round of the NCAA Tournament.

Here’s why we think they have a fighting chance against Missouri.

How to watch Princeton vs. Missouri

Gametime: 6:10 pm Eastern

TV: TNT

Live Stream: March Madness Live app, fuboTV, Sling, YouTube TV, Hulu + Live TV

Princeton (+6.5) over Missouri

New Jersey’s Tigers have been at their best when the least has been expected of them.

This season, Princeton is 5-1 against the spread as an underdog, most recently pulling outright upsets over Yale in the Ivy League title game and the stunner over Arizona in the first round.

The past two wins have come against the best two defenses and rebounding units Princeton played this season.

Mitch Henderson’s group will face easier matchups against a Missouri team that ranks 203rd in the nation in opponent shooting percentage and 359th in rebounding rate.

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Don’t discount the outright upset.

Three of the past four 15-seeds to win their first round game also reached the Sweet 16.